Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility

نویسندگان

  • Kenneth W Witwer
  • Carolina Soekmadji
  • Andrew F Hill
  • Marca H Wauben
  • Edit I Buzás
  • Dolores Di Vizio
  • Juan M Falcon-Perez
  • Chris Gardiner
  • Fred Hochberg
  • Igor V Kurochkin
  • Jan Lötvall
  • Suresh Mathivanan
  • Rienk Nieuwland
  • Susmita Sahoo
  • Hidetoshi Tahara
  • Ana Claudia Torrecilhas
  • Alissa M Weaver
  • Hang Yin
  • Lei Zheng
  • Yong Song Gho
  • Peter Quesenberry
  • Clotilde Théry
چکیده

An editorial describing “minimal experimental requirements for definition of extracellular vesicles (EVs)”, or more simply “minimal information for studies of EVs (MISEV)” was published in the Journal of Extracellular Vesicles in late 2014 [1]. Similar to guidelines in other scientific fields [2–4], “MISEV2014”, as we will call it here, provided recommendations on experimental methods and minimal information in reporting. Specifically, three key areas were addressed: EV isolation/purification, EV characterization and EV functional studies (see Text Box 1).

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2017